tag:blogger.com,1999:blog-23072522010729097732024-03-14T07:14:43.694-07:00Neuro SpeedNeuro Speedhttp://www.blogger.com/profile/06920432181720158638noreply@blogger.comBlogger285125tag:blogger.com,1999:blog-2307252201072909773.post-37959021282661931482019-02-01T17:20:00.000-08:002019-02-01T17:20:44.378-08:00Risk of Stroke by Geographic Region<span style="font-family: Georgia, Times New Roman, serif; font-size: x-large;"> <span style="color: purple;"> The <span style="background-color: yellow;">lifetime risk of stroke for men and women</span> over age 25 globally is <span style="background-color: yellow;">25%.</span></span></span><br />
<span style="color: purple; font-family: Georgia, Times New Roman, serif; font-size: x-large;"> In an NEJM study, large geographic variations were found. In 2016, the <span style="background-color: yellow;">highest-risk regions were East Asia (38.8%), Central Europe (37.1%), and Eastern Europe (31.6%)</span>. The <span style="background-color: yellow;">lowest</span> region of stroke risk was <span style="background-color: yellow;">sub-Saharan Africa (11.8%).</span></span><br />
<span style="color: red; font-family: Georgia, Times New Roman, serif; font-size: x-large;">NEJM 20 Dec 2018; 379:2429-2437</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-59656226931541459882019-02-01T16:59:00.001-08:002019-02-01T16:59:15.286-08:00UH OH: A History of Drug Treatment for ADHD dramatically Increase Risk of Parkinson's Disease<span style="font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"> <span style="color: #a64d79;">From a report from the Center for Disease Control and Prevention 3/4 of children with ADHD are prescribed amphetamine or methylphenidate. A study from the U of Utah school of Dentistry provides provocative findings. <span style="background-color: yellow;">Individuals with ADHD are 2-3 times more likely to develop Parkinson's disease than those without.</span></span></span><br />
<span style="color: #a64d79;"><span style="font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"> Further, those with ADHD who were</span><span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif; font-size: x-large;"> </span><span style="background-color: yellow;"><span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif; font-size: x-large;">prescribed psychostimulant drugs were 8 to 9 times more likely to develop Parkin</span><span style="font-family: "Helvetica Neue", Arial, Helvetica, sans-serif; font-size: x-large;">son's.</span></span></span><br />
<span style="background-color: yellow; font-family: "Helvetica Neue", Arial, Helvetica, sans-serif; font-size: x-large;"><span style="color: blue;">Neuropsychopharmacol 2018;43(11):2548-2555</span></span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-86305172634413301532019-02-01T16:42:00.000-08:002019-02-01T16:42:39.453-08:00Bullying Hurts the Brain !<span style="font-family: Arial, Helvetica, sans-serif; font-size: x-large;"> <span style="color: purple;"> Investigators at King's College London in their IMAGEN project found that <span style="background-color: yellow;">bullying</span> was <span style="background-color: yellow;">associated with decreases in the volume of</span> particular <span style="background-color: yellow;">brain structures</span> namely the caudate and putamen. These structural changes could <span style="background-color: yellow;">increase</span> the likelihood of <span style="background-color: yellow;">mental illness</span> such as higher levels of generalized <span style="background-color: yellow;">anxiety</span> identified in their study population by age 19.</span></span><br />
<span style="color: purple; font-family: Arial, Helvetica, sans-serif; font-size: x-large;">Synonymous terms in this study: bullying and peer victimization.</span><br />
<span style="color: #3d85c6; font-family: Arial, Helvetica, sans-serif; font-size: x-large;"><i>Mol Psychiatry.</i> 12 Dec 2018</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-44815891915858110122019-02-01T16:31:00.000-08:002019-02-01T16:31:05.895-08:00Improve your Memory: DANCE and Tai Chi !<span style="font-family: Verdana, sans-serif; font-size: x-large;"> <span style="color: #cc0000;">In an analysis of from 32 randomized, controlled trials mind-body exercises, particularly <span style="background-color: yellow;">dance and tai chi</span>, was shown to <span style="background-color: yellow;">improve</span> learning, verbal fluency, working memory, cognitive flexibility and <span style="background-color: yellow;">global cognition in older adults.</span></span></span><br />
<span style="color: #cc0000; font-family: Verdana, sans-serif; font-size: x-large;"> Further <span style="background-color: yellow;">only MODERATE exercise</span> intensity of 60-120 minutes per week was <span style="background-color: yellow;">necessary to significantly increase global cognitive scores.</span></span><br />
<span style="font-family: Verdana, sans-serif; font-size: x-large;"><i>J AM Geriatr Soc</i>. 2018 Dec 18</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-32267435464095249302018-12-31T17:20:00.000-08:002018-12-31T17:20:37.473-08:00African Folk Remedy's for Seizures Molecular Mechanism discovered<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"> <span style="color: blue;"><span style="background-color: yellow;">The leaf extract from the shrub <i>Malotus oppositifolius</i> helps to control seizures.</span> Now researchers at UC Irvine have identified two components from the leaf extract activate KCNQ2/3, a potassium channel essential for controlling electrical activity in the brain. These two components together are highly effective at activating these potassium ion channels and preventing seizures.</span></span><br />
<span style="color: blue; font-family: Trebuchet MS, sans-serif; font-size: x-large;"> Isovaleric acid, a component of valerian root is one of these active compounds in <span style="background-color: yellow;">this African folk remedy</span>.</span><br />
<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"> Amazing.</span><br />
<span style="color: #741b47; font-family: Trebuchet MS, sans-serif; font-size: x-large;">Nat Comun. 2018;9(1):3845</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-44007064000684805092018-12-31T16:30:00.000-08:002018-12-31T16:30:23.073-08:00Stiff Aorta Predicts Dementia<span style="font-family: Georgia, Times New Roman, serif; font-size: x-large;"> <span style="color: red;">From the Cardiovascular Health Study, researchers found that individuals with<span style="background-color: yellow;"> high carotid-femoral pulse wave velocities (consistent with increased aortic stiffness) were 60% more likely to develop dementia </span>during the following 15 years.</span></span><br />
<span style="color: blue; font-family: Georgia, Times New Roman, serif; font-size: x-large;"><i>J Alzheimers Dis</i>. 2018;66(1):297-306</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-64549887303405496382018-12-31T16:19:00.000-08:002018-12-31T16:19:54.055-08:00High Cortisol Associated with Impaired Memory<span style="font-size: x-large;"> <span style="color: #660000;"> <span style="font-family: Arial, Helvetica, sans-serif;">From the Framingham heart study, researchers found that middle-aged individuals with <span style="background-color: yellow;">high levels of cortisol </span>in their blood <span style="background-color: yellow;">have impaired memory</span> compared to those with normal cortisol.</span></span></span><br />
<span style="font-size: x-large;"><span style="font-family: Arial, Helvetica, sans-serif;"> Hmm...stay tuned.</span></span><br />
<span style="font-size: x-large;"><span style="font-family: Arial, Helvetica, sans-serif;"><i>Neurology</i>. 2018 Oct 24</span></span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-65895007280516819602018-12-31T16:07:00.000-08:002018-12-31T16:07:54.488-08:00Good Sleep Quality to Improve Sport-related Concussion in the Young<span style="font-size: x-large;"> <span style="color: purple;">From researchers out of Texas, young athletes with <span style="background-color: yellow;">good sleep quality after a sports-related concussion are more likely to recover within two weeks</span> compared to those with poor quality sleep.</span></span><br />
<span style="color: purple; font-size: x-large;"> Guide to parent's to improve their child's sleep: avoid electronics one hour before bedtime, establish a regular sleep schedule and encourage 8-10 hours of sleep each night.</span><br />
<span style="color: #741b47; font-size: x-large;">American Academy of Pediatrics 2018 Annual Conference</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-32486301787532249742018-12-31T15:53:00.001-08:002018-12-31T15:53:24.725-08:00Migraine Prevention in Pregnancy<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"> <span style="color: #3d85c6;">A review of the literature from researchers at UCSF indicate that <span style="background-color: yellow;">only amitriptyline and LOW DOSE propanolol</span> (ie, 30-40mg per day) have sufficient data to classify them as <span style="background-color: yellow;">compatible during pregnancy</span>. Higher doses of propanolol may cause intra-uterine growth retardation.</span></span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-80421185458821253912018-12-31T15:40:00.002-08:002018-12-31T15:40:59.298-08:00Contact Lawmakers to Support Brain Research !<span style="font-family: Verdana, sans-serif; font-size: x-large;"> <span style="color: red;">From researchers in the Netherlands, <span style="background-color: yellow;">half of all women and one-third of all men will develop dementia, stroke or Parkinsonism.</span></span></span><br />
<span style="color: red; font-family: Verdana, sans-serif; font-size: x-large;"> Please support the American Academy of Neurology's (and this neurologist's) advocacy efforts to continue funding of the BRAIN (Brain Research through Advancing Innovative Neurotechnologies) initiative by contacting your representatives in congress and the senate.</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-55107876856537372152018-12-31T15:26:00.002-08:002018-12-31T15:26:30.390-08:00 Sing to Feel and Move Better with Parkinson's !<span style="font-size: x-large;"> <span style="color: purple;"> From kinesiology researchers at Iowa State,<span style="background-color: yellow;"> singing improves motor symptoms, mood and decreases physiologic indicators of stress in patient's with Parkinson's disease</span>. Also improved were swallowing and respiratory control. </span></span><br />
<span style="font-size: x-large;"><span style="color: purple;"> The mechanism is unkown.</span></span><br />
<span style="color: purple; font-size: x-large;">Society for Neuroscience 2018</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-1459510170405503922018-12-29T16:52:00.000-08:002018-12-29T16:52:28.224-08:00How Often are Staring Spells in Kids due to Seizures ?<span style="font-family: Georgia, Times New Roman, serif; font-size: x-large;"> </span><span style="font-family: Georgia, "Times New Roman", serif; font-size: x-large;"> <span style="color: blue;"><span style="background-color: yellow;">Staring spells</span> are not uncommon in kids. From researchers at Emory, 2,818 patients were reviewed that presented to the new onset pediatric seizure clinic for evaluation of staring spells.</span></span><br />
<span style="color: blue; font-family: Georgia, Times New Roman, serif; font-size: x-large;"> About <span style="background-color: yellow;">half were found to have epilepsy</span>.</span><br />
<span style="font-family: Georgia, Times New Roman, serif; font-size: x-large;">Annual Meeting of Child Neurology 2018</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-10472203928057003222018-12-29T16:26:00.001-08:002018-12-29T16:26:38.081-08:00Stuttering: Major Breakthrough in Treatment !<span style="font-family: Arial, Helvetica, sans-serif; font-size: x-large;"> <span style="color: #38761d;">From researchers in Houston, nine <span style="background-color: yellow;">patients that had stuttering speech</span> aged 18 to 80 were <span style="background-color: yellow;">treated</span> for 10 days <span style="background-color: yellow;">using</span> noninvasive <span style="background-color: yellow;">magnetic brain stimulation</span> (TRPMS, invented at Weill Cornell in New York). <span style="background-color: yellow;">All</span> study participants <span style="background-color: yellow;">significantly improved in fluency</span>. In other words, it works.</span></span><br />
<span style="color: #38761d; font-family: Arial, Helvetica, sans-serif; font-size: x-large;"> Next will be followup studies looking at functional MRI changes in treated individuals and an assessment of best treatment frequency.</span><br />
<span style="font-family: Arial, Helvetica, sans-serif; font-size: x-large;">ANA Annual Meeting 2018</span><br />
<span style="font-family: Arial, Helvetica, sans-serif; font-size: x-large;">More info at Seraya Medical Systems</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-27908461748595373012018-12-29T16:04:00.000-08:002018-12-29T16:04:22.831-08:00Tremor in PD? Skip the Knife <span style="font-family: Verdana, sans-serif; font-size: x-large;"> <span style="color: #990000;">From neuropsychologists at the U of Virginia, <span style="background-color: yellow;">focused ultrasound thalamotomy</span> (that strategically makes a hole deep in the brain) <span style="background-color: yellow;">improves the quality of life in patient's with drug resistant tremor associated with Parkinson's</span> disease.</span></span><br />
<span style="font-family: Verdana, sans-serif; font-size: x-large;"><i>Neurology</i> 2018. 91(14):e1275-e1284</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-66828110373478322442018-12-29T15:38:00.000-08:002018-12-29T15:38:29.442-08:00Concussion or Mild Traumatic Brain Injury Increases Risk of Suicide<span style="font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"> <span style="color: blue;">From a review of the literature from 1963 to 2017, researchers in Toronto found that experiencing a <span style="background-color: yellow;">concussion or mild traumatic brain injury was associated with a twofold higher risk of suicide</span> as well as suicide attempts and suicidal ideation.</span></span><br />
<span style="color: purple; font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"><i>JAMA Neurol</i>. 2018 Nov 12</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-61564299388938854992018-12-29T15:29:00.000-08:002018-12-29T15:29:40.643-08:00Appendectomy to Decrease Risk of Parkinson's Disease ? Maybe...Stay Tuned<span style="font-family: Arial, Helvetica, sans-serif; font-size: x-large;"> <span style="color: purple;">The vermiform appendix was once considered to be a vestigial (left over, no longer used) organ. There is now evidence that the appendix plays a major role in the regulation of the immune system especially regulation of gut bacteria.</span></span><br />
<span style="color: purple; font-family: Arial, Helvetica, sans-serif; font-size: x-large;"> From the largest of these epidemiologic related studies that reviewed the health records of 1.6 million Swedes that <span style="background-color: yellow;">the incidence of PD was 19.3% lower in those that had their appendix removed</span>.</span><br />
<span style="color: purple; font-family: Arial, Helvetica, sans-serif; font-size: x-large;"> This data suggests that the appendix may be a reservoir of alpha-synuclein (the protein that accumulates in excess in the brain's of Parkinson's and related conditions (DLB).</span><br />
<span style="color: purple; font-family: Arial, Helvetica, sans-serif; font-size: x-large;"> Since only 1% of the population gets PD it has been postulated that some, as yet unknown, confluence of events (such as an environmental trigger) that alters the gut microbiome decades before the disease is evident that mediates the risk of Parkinson's.</span><br />
<span style="color: blue; font-family: Arial, Helvetica, sans-serif; font-size: x-large;"><i>Sci Transl Med</i>. 2018;10(465)</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-66792940808084609052018-11-24T17:40:00.000-08:002018-11-24T17:40:56.452-08:00Cause Found for Polio-like Acute Flacid Myelitis in Children<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"> Sporadic outbreaks of <span style="background-color: yellow;">Enterovirus (EV) type A71 cause several syndromes</span>, mostly affecting children less than 5 years of age and occur in spring to fall months in North America.</span><br />
<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"> Syndromes include : pharyngitis, gastroenteritis, exanthems such as the so-called hand/foot/and mouth disease <span style="background-color: yellow;">and the severe neurologic syndromes including meningitis, encephalitis, and AFM with flaccid paralysis.</span></span><br />
<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"> <span style="background-color: yellow;">EV-A71 was identified in nasopharyngeal or rectal specimens BUT very Rarely from spinal fluid.</span></span><br />
<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"><i>MMWR Morb Wkly Rep 2018 Sep 14;67:107</i></span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-6229007017228771142018-11-24T17:25:00.002-08:002018-11-24T17:25:41.473-08:00Prevalence of Low Back Pain has Increased 100% in the Last Decade<span style="font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"> <span style="color: purple;"> Low back pain is a major cause of disability and is a major public health issue.</span></span><br />
<span style="color: purple; font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"> Occupational exposure that includes hard work, frequent standing, sitting, bending, twisting and concentration demands are risk factors for low back pain (<i>Occup Environ Med 1997;54:742</i>). </span><br />
<span style="color: purple; font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;">The prevalence of low back pain has increased 100% in the last decade (<i>F1000Research 2016;5:1530</i>)</span><br />
<span style="color: purple; font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"> The finding of this study provides significant evidence <span style="background-color: yellow;">Lumbosacral Radiculopathy can be considered a work related disease especially those jobs that depend on exposure to bending of the trunk, carrying and lifting.</span></span><br />
<span style="color: purple; font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"> Of note, there was NOT an association between professional driving or sitting and LRS.</span><br />
<span style="font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"><i>Neurology 2018 Sep 18;91:558</i></span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-37883870043038614152018-11-24T17:12:00.001-08:002018-11-24T17:12:34.549-08:00TAI CHI Most Effective For Fall Prevention<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"> <span style="color: blue;">Researchers in Oregon studied elders at high risk for falls. Tai ji quan (better known as <span style="background-color: yellow;">Tai Chi</span>) was found to be <span style="background-color: yellow;">superior at decreasing risk of falls</span> in this population compared to previously emphasized mutimodal exercise : (strengthening, aerobic training, balance training and flexibility exercises) and stretching.</span></span><br />
<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"><i>JAMA INT MED 2018 Sep 10</i></span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-7027907630061475312018-10-19T19:25:00.000-07:002018-10-19T19:25:04.866-07:00Areas in Brain Actually Identified that are Associated with Analgesia In Nerve Pain with CANNABIS. WOW.<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"> <span style="color: #6aa84f;">The anterior cingulate gyrus <span style="background-color: yellow;">(ACC)</span> <span style="background-color: yellow;">and</span> dorsolateral pre-frontal cortex <span style="background-color: yellow;">(DLPC)</span> <span style="background-color: yellow;">are</span> functionally <span style="background-color: yellow;">involved in</span> <span style="background-color: yellow;">THC-induced analgesia in chronic neuropathic pain</span>.</span></span><br />
<span style="font-family: Trebuchet MS, sans-serif; font-size: x-large;"> <i>Neurology</i>. 2018;91:e1285-e1294</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-9133092681066854342018-10-19T19:10:00.000-07:002018-10-19T19:10:21.388-07:00Light Exposure may Improve Agitation, Mood and Sleep in Dementia<span style="font-family: Verdana, sans-serif; font-size: x-large;"> <span style="color: red;">LED table lights and individual room lights were placed where patients spent most of their waking hours. The lights were turned on when folks woke up and remained on until 6 PM.</span></span><br />
<span style="color: red; font-family: Verdana, sans-serif; font-size: x-large;"> <span style="background-color: yellow;">Exposure to light</span> stimulates the circadian system early in the day significantly <span style="background-color: yellow;">decreasing</span> scores for <span style="background-color: yellow;">sleep disturbances, agitation and depression</span> compared with placebo.</span><br />
<span style="font-family: Verdana, sans-serif; font-size: x-large;"><i>Sleep Health</i>. 2017;3(3):204-215</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-81575672477116589562018-10-19T18:59:00.003-07:002018-10-19T18:59:24.492-07:00Cardiovascular Risk Increases with Binge Drinking in Men<span style="font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"> <span style="color: purple;"> <span style="background-color: yellow;">Higher blood pressure, higher blood sugar, and higher cholesterol are associated with</span> young men <span style="background-color: yellow;">that binge</span> drank as many as 12 times per year compared with non-binge drinkers.</span></span><br />
<span style="color: purple; font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"> Binge drinking women did not have affected systolic blood pressures or total cholesterol.</span><br />
<span style="font-family: Helvetica Neue, Arial, Helvetica, sans-serif; font-size: x-large;"><i>J Am Heart Assoc</i>. 2018;7(13)</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-55918402347688980872018-10-19T18:49:00.003-07:002018-10-19T18:49:58.497-07:00Eye Conditions Affect Alzheimer's Risk<span style="font-family: Arial, Helvetica, sans-serif; font-size: x-large;"> <span style="color: blue;"> People with recent diagnoses of <span style="background-color: yellow;">diabetic retinopathy and glaucoma</span> as well as well established age-related <span style="background-color: yellow;">macular degeneration</span> may have an <span style="background-color: yellow;">increased risk of Alzheimer's disease</span>.</span></span><br />
<span style="color: blue; font-family: Arial, Helvetica, sans-serif; font-size: x-large;"> Cataract diagnosis was not a risk factor for AD.</span><br />
<span style="font-family: Arial, Helvetica, sans-serif; font-size: x-large;"><i>Alzheimers Dement</i>. 2018 Aug 2</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-22803997852968565142018-09-04T17:28:00.000-07:002018-09-04T17:28:42.630-07:00New Treatment for Early Memory Troubles ?<span style="font-family: Georgia, Times New Roman, serif; font-size: x-large;"> <span style="color: #741b47;">There is a clinical trial in phase 3 led by a researcher at Wake Forest which found earlier that participants that took a <span style="background-color: yellow;">long-acting intranasal insulin demonstrated improved cognition in adults with mild cognitive impairment.</span></span></span><br />
<span style="color: #741b47; font-family: Georgia, Times New Roman, serif; font-size: x-large;"> Results will be made public in 12 months. Fingers crossed for some kind of breakthrough.</span><br />
<span style="color: #741b47; font-family: Georgia, Times New Roman, serif; font-size: x-large;"> MCI (mild cognitive impairment) is a neurological disorder that occurs in older adults which manifests as cognitive impairment BUT NOT impairment in activities of daily living.</span><br />
<span style="font-family: Georgia, Times New Roman, serif; font-size: x-large;">First reported in <i>J Alzheimers Dis</i> 2015;44(30:897-906 20</span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0tag:blogger.com,1999:blog-2307252201072909773.post-44135866791189573632018-09-03T18:01:00.000-07:002018-09-03T18:01:28.226-07:00Low Fasting Insulin Doubles the Risk of Dementia<span style="font-family: Verdana, sans-serif; font-size: x-large;"> <span style="color: #990000;">A recent study confirmed a shocking finding of 14 years ago (which studied 2,568 Japanese American men) that <span style="background-color: yellow;">low fasting insulin in middle age doubles the risk of dementia</span> in later years.</span></span><br />
<span style="color: #990000; font-family: Verdana, sans-serif; font-size: x-large;"> Insulin deficiency itself is one of the key components of Alzheimer's and that low levels of insulin or insulin resistance are associated with poor brain function.</span><br />
<span style="color: #990000; font-family: Verdana, sans-serif; font-size: x-large;"> These researchers concluded that low insulin must involve a new pathway to dementia different from the well-known metabolic pathway in diabetes.</span><br />
<span style="color: #990000; font-family: Verdana, sans-serif; font-size: x-large;"> Reduced brain metabolism may not be the factor linking low insulin to dementia but rather it may be the role of insulin as a growth factor maintaining the function of neurons that may be vital.</span><br />
<span style="color: blue; font-family: Verdana, sans-serif; font-size: x-large;"><i>Neurology</i> 2018:Epub 2018 Jul 11</span><br />
<span style="font-family: Verdana, sans-serif; font-size: x-large;"> </span>Dr.Christopher Prusinskihttp://www.blogger.com/profile/12258584613538580235noreply@blogger.com0