Monday, May 10, 2010


The American academy of Neurology has updated its 1999 guidelines to the treatment and managegment of amyotrophic lateral sclerosis (ALS), highlights include:
1.Riluzole should be offered to slow disease progression
2.PEG tube to stabilize weight and prolong survival
3.NIV (non-invasive ventilation) for respiratory insufficiency to slow the decline in FVC (forced vital capacity) and improve quality of life
4.Creatine(5-10 mg) or high-dose vitamin E should not be given
5.Sialorrhea (increased salivation) can be reduced with botox type B
Neurology 2009;73:1218-1226 and 1227-1233

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