Prenatal acetaminophen was found to be associated with increased risks of psychopathology such as conduct problems, hyperactivity problems and emotional symptoms (ADHD). (JAMA Pediatr 2016 Aug 15;[pub])
Common causes for taking acetaminophen during pregnancy include infection and fever both of which can produce epigenetic and brain changes according to an animal study. (Biol Psychiatry 2016 Aug 12;[e-pub])
Animal data also reveal that prenatal acetaminophen, even without inflammation, can disrupt neurodevelopment. (Toxicol Sci 2014;138-139)
These studies suggest there should be increased efforts to vaccinate women against influenza and to encourage them to avoid exposure to flu infected individuals.