Saturday, November 19, 2016

Treatment Therapies For Fatigue In MS

  Primary fatigue (unique to multiple sclerosis) involves no precipitating activity, is worsened by heat or humidity, and is worse in the early afternoon. 40 % of MS patients report it as their most disabling symptom. This fatigue may be constant in 30 % of affected individuals.
  The cause of primary fatigue is unknown.
  Treatment options include : cooling, aerobic and strength training, energy conservation, mindfulness, relaxation therapy, magnetic therapy, transcranial stimulation, and drugs.
  Drug therapy to treat fatigue include : amantadine, modafinil, armodafinil, gingko biloba, methylphenidate and amphetamines.
  Comorbid conditions must be addressed : depression, anemia, thyroid disease, disrupted sleep, medication side effects, motor disability with increased energy use. (Continuum 2016;22(3):815-836

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