The leaf extract from the shrub Malotus oppositifolius helps to control seizures. Now researchers at UC Irvine have identified two components from the leaf extract activate KCNQ2/3, a potassium channel essential for controlling electrical activity in the brain. These two components together are highly effective at activating these potassium ion channels and preventing seizures.
Isovaleric acid, a component of valerian root is one of these active compounds in this African folk remedy.
Nat Comun. 2018;9(1):3845