Colicky Infants at Risk for Childhood Migraine

  Children that presented to the ER with migraine were 6x more likely to have a history of colic during infancy.
  It is theorized that colic may represent sensitization of the perivascular nerve terminals in the gut.
   Sadly, the brain-gut relation remains one of the least understood and least researched areas of medicine.
JAMA 2013;309(15):1607-1612