Monday, March 21, 2016

Immunologic Profile in MS Patients Altered with High Dose Vitamin D

   Those with low Vitamin D levels have been shown to have have an increased risk of developing multiple sclerosis in previous studies as well as an increased number of brain lesions on MRI. NEJM JW Neurol Dec 2015, JAMA Neurol 2015;72:1458
  A newer study revealed reduced percentages of IL17+CD4+T cells and effects memory cells CD4+ in patients that received 10,400 IU of vitamin D3 daily.
Neurology 2015 Dec 30

Sunday, March 13, 2016

Potential Treatment for Traumatic Brain Injury and PTSD

  Methylphenidate improved attention, post concussion symptoms and PTSD symptoms. Galantamine improved episodic memory. Both drugs improved depression in TBI and PTSD patients.
Neuropsychopharmacology 2015 Sept 11

Increased Risk of MS in Children In Pregnant Women with Low Vitamin D3

  The children born to women with low vitamin D3 levels were found to be at double the risk of developing multiple sclerosis.
JAMA Neurol. March 7,2016

Modest Seafood intake Decreased Alzheimer's Risk

  Even a single seafood serving a week had a neuroprotective benefit against the development of neurofibrillary tangles and amyloid deposits in people that carry the apolipoprotein e4 risk gene for Alzheimer's. The same is NOT true for those that do not carry the APOE e4 gene. 
  Interestingly, that same population studied also were found to have increased mercury in their brains WITHOUT an adverse effect pathologically.
JAMA 2016;315(5):465-466