Sunday, December 4, 2011
Journal of Alzheimer's Disease online Feb 14 2011
Annals of Neurology online April 2011
Arch Neurol 2011; E-Pub Sept 12 2011
J Clin Sleep Med, 2010; 6 (6): 605-608
Med Hypotheses. 2011 ; 76 (2) :208-213
NEURON 2011; E-pub Sept 21 2011
Wednesday, September 7, 2011
Statin therapy appears to reduce the risk of recurrent stroke among patients with diabetes or the metabolic syndrome to the same degree that it does in patients who have neither disorder, according to a planned post hoc analysis of data collected in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels clinical trial (SPARCL).
Tuesday, September 6, 2011
Feinberg School scientists found the cause of ALS by discovering a protein, ubiquilin2, whose critical job is to recycle damaged or misfolded proteins in motor and cortical neurons and shuttle them off to be reprocessed. In people with ALS, Feinberg researchers found ubiquilin2 isn’t doing its job. As a result, the damaged proteins and ubiquilin2 loiter and accumulate in the motor neurons in the spinal cord and cortical and hippocampal neurons in the brain. The protein accumulations resemble twisted skeins of yarn -- characteristic of ALS -- and cause the degeneration of the neurons. Researchers found ubiquilin2 in these skein-like accumulations in the spinal cords of ALS cases and in the brains of ALS/dementia cases.
Wednesday, July 27, 2011
The protein amyloid beta1-42, or A1-42, which has previously been considered a CSF biomarker for Alzheimer’s disease, was not a predictive factor in this study.