New Alzheimer's Biomarker

Researchers found that the best predictor of whether someone would develop Alzheimer’s disease was a combination of cerebrospinal fluid sAPP (soluble amyloid precursor protein ), CSF tau protein (an established marker of brain cell damage) and the age of the individual. When these factors were combined, the results were roughly 80 percent accurate in predicting whether the disease would develop.

The protein amyloid beta1-42, or A1-42, which has previously been considered a CSF biomarker for Alzheimer’s disease, was not a predictive factor in this study.

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