Joshua Shulman,MD,PhD , instructor of neurology at Harvard medical school used the drosophila model for Alzheimer's disease to determine how variants function. The drosophila tauopathy model, which exhibits age-dependent neurodegeneration, decreased lifespan and hyperphophorylated and misfiled tau protein. The model is used to functionally screen candidate genes in AD which may lead to sooner treatment options for afflicted patients.
Arch Neurol 2011; E-Pub Sept 12 2011
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