ALS-AAN NEW GUIDELINES

The American academy of Neurology has updated its 1999 guidelines to the treatment and managegment of amyotrophic lateral sclerosis (ALS), highlights include:

1.Riluzole should be offered to slow disease progression

2.PEG tube to stabilize weight and prolong survival

3.NIV (non-invasive ventilation) for respiratory insufficiency to slow the decline in FVC (forced vital capacity) and improve quality of life

4.Creatine(5-10 mg) or high-dose vitamin E should not be given

5.Sialorrhea (increased salivation) can be reduced with botox type B

Neurology 2009;73:1218-1226 and 1227-1233