According to an animal study, disruption in sleep patterns and it's consequent threat to their well-being occurs in mammals because advancing age impairs the ability of the circadian clock to reset itself when exposed to light.
Further, age results in a dramatic reduction in sensitivity to light in the suoprachiasmatic nucleus (SCN), the part of the brain that controls circadian rhythms.
In one SCN pathway studied in mice, a glutamate receptor (NMDA) which is used to transmit light information became less effective in resetting the circadian clock and exhibited a markedly decreased presence as a part of the aging process.
Neurobiol Aging. 2018 Feb 20
Showing posts with label SCN and aging. Show all posts
Showing posts with label SCN and aging. Show all posts
Thursday, August 16, 2018
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