Pancreatic,liver and lung cancer were found to decrease the risk of Alzheimer's disease by 10 to 51%.Conversely, melanoma and prostate CA were associated with an increased risk of AD.
Further, cancer patients that received radiation or chemotherapy had an added reduced risk of AD of 17 to 23%.
Neurology 2013;81(4):322-328
BMJ 2012 Mar 12;344:e1442
Showing posts with label abeta amyloid and radiation exposure. Show all posts
Showing posts with label abeta amyloid and radiation exposure. Show all posts
Wednesday, December 4, 2013
Monday, April 22, 2013
Travel to Mars but Loose Your Marbles ?
Researchers from URMC in cooperation with the NASA Space Radiation Lab at Brookhaven exposed double transgenic mice ( with APP and Presenilin mutations), that were destined to develop Alzheimer's pathological changes anyway, to Iron-56. Six months after 10 and 100 cGy radiation at 1GeV/u the mice displayed impairment on behavioral studies. After sacrifice, there was evidence of accelerated beta amyloid deposition.
This is the first study to demonstrate that HZE particle radiation can increase beta amyloid plaque pathology.
Studies are underway with normal mice to see if the effects can be duplicated.
PLoS One 2012;7(12):e53275. E-pub 2012 Dec 31
This is the first study to demonstrate that HZE particle radiation can increase beta amyloid plaque pathology.
Studies are underway with normal mice to see if the effects can be duplicated.
PLoS One 2012;7(12):e53275. E-pub 2012 Dec 31
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