New Non-Drug Treatment of Essential Tremor

  Cala Health, based in California has received FDA approval (April 2018) for a wearable device to treat the inherited tremor called essential tremor.
  The Cala ONE device includes electrodes worn on the wrist to stimulate median and radial nerves.
  The device captures 20 seconds of a patient's postural tremor and delivers a stimulation pattern based on a patient's peak tremor frequency.
CalaHealth.com

Ultrasound Thalamotomy Treatment For Essential Tremor

  From the U of VirginiaCOM 15 study patients with essential tremor were treated with MRI-guided focused high-intensity ultrasound waves (sonification) to ablate the ventral us intermedius nucleus of the thalamus. Significant improvement was seen in all patients that were heretofore unresponsive to drug treatment (typically 50% of patients with ET which is inherited).
  The down side: this treatment, unlike deep brain stimulation, is irreversible and therefore adverse events are permanent including four patients in this study that suffered persistent paresthesias.
  The up side: US thalamotomy may be applicable to other disorders : brain tumors, other movement disorders, epilepsy and central pain disorders.
NEJM 2013;369:640-648
Lancet Neurology 2013;12(5):462-468