From the American Academy of Neurology annual meeting in San Diego last week, autopsied brains from the Honolulu-Asia Aging Study revealed that people that had been treated with beta blockers alone (an older method of treating hypertension) showed fewer microinfarcts, less brain atrophy and fewer lesions of the type seen in Alzheimer's disease.
Researchers concluded that Beta-blocker use is associated with a lower risk of developing cognitive impairment and decline in elderly Japanese American men.
As previously reported, elevated blood pressure is a known risk factor for Alzheimer's disease and cognitive impairment.
The surprising results of this study will be important for "hypothesis generation" about how beta blockers might influence Alzheimer's neuropathology and cognition later in life.
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