Five retired profesional football players age 45 and older with a history of concussions underwent PET scanning after IV injections of FDNNP, a chemical marker which binds to amyloid beta and tau .
Compared with healthy males, the former pro athletes had elevated levels of FDNNP in the amygdala and subcortical regions of their brains.
Additionally, higher levels of FDNNP correlated with a higher number of reported concussions.
American Journal of Geriatric Psychiatry online Jan 22, 2013
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